Causes or Cures

Dog Longevity: Developing Drugs that Extend a Dog's Life, with Dr. Brennen McKenzie

May 11, 2023 Dr. Eeks/Dr. McKenzie Episode 140
Causes or Cures
Dog Longevity: Developing Drugs that Extend a Dog's Life, with Dr. Brennen McKenzie
Show Notes

In this episode of Causes or Cures, Dr. Eeks chats with Dr. Brennen McKenzie, a veterinarian, epidemiologist and Director of Veterinary Medicine at Loyal, a clinical-stage veterinary medicine company developing drugs to prolong the lifespan and healthspan of dogs.
He will discuss the aging process in dogs, age-related biomarkers, and the link between dog size (big vs small) and lifespan. He will explain what a dog's "methylation age" is, how that relates to "epigenetics" and  how that is similar to and differs from a dog's chronological age. Then he will talk about some of the studies Loyal is conducting and discuss some of the drugs they are developing to prolong a dog's lifespan. (You may be able to enroll your dog in a study, right from home, if interested.) Finally, he'll describe when he thinks we might see a "noticeable" difference in a dog's lifespan. 

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